São Bartolomeu (Portuguese for Saint Bartholomew) may refer to the following places:
in Portugal São Bartolomeu (Borba), a civil parish in the municipality of Borba São Bartolomeu (Coimbra), a civil parish in the municipality of Coimbra São Bartolomeu (Vila Viçosa), a civil parish in the municipality of Vila Viçosa São Bartolomeu de Regatos, a civil parish in the municipality of Angra do Heroísmo, Azores São Bartolomeu dos Galegos, a civil parish in the municipality of Lourinhã São Bartolomeu de Messines, a civil parish in the municipality of Silves
in Brazil São Bartolomeu River, a river in Goiás state