NAFC may refer to

Organizations North America North American Football Confederation Northwest Atlantic Fisheries Centre, of Canada National Association of Free Clinics, of the U.S. National Association For Continence, of the U.S. National Association of Friendship Centres - part of the Friendship Centre Movement of Canada National Anthropological Film Center, the previous name of the Human Studies Film Archives, part of the Smithsonian Institution in the U.S. Nash Finch Company (NASDAQ symbol: NAFC), a U.S. food distribution company

Australia National Aerial Firefighting Centre North Adelaide Football Club, Australian rules football team in the South Australian National Football League

Elsewhere NAFC Marine Centre, a constituent institution of the University of the Highlands and Islands in Scotland