Big Brother 16 is the sixteenth season of various versions of Big Brother and may refer to:
Big Brother 16 (U.S.), the 2014 edition of the U.S. version Big Brother 16 (UK), the 2015 edition of the UK version Gran Hermano 16, the 2015 edition of the Spanish version Big Brother Brasil 16, the 2016 edition of the Brazilian version Bigg Boss 16, sixteenth season of Big Brother in India in Hindi
See also Big Brother (franchise) Big Brother (disambiguation)