Scm-like with four mbt domains 1 is a protein that in humans is encoded by the SFMBT1 gene.

Function This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]. It encodes a transcriptional repressor protein. The SFMBT1 protein's interaction with cancers is unclear, but elevated levels have been recorded in some renal cancers.

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