Menéndez Márquez is a Spanish surname. In English the name is often spelled without the diacritics. It may refer to:
Francisco Menéndez Márquez (d. 1649), royal treasurer and interim governor of Spanish Florida Juan Menéndez Márquez (d. 1627), royal treasurer and interim governor of Spanish Florida Pedro Menéndez Márquez (d. 1600), governor of Spanish Florida Tomás Menéndez Márquez (1643-1706), royal accountant of Spanish Florida