Papoulias (or Papoulia, maiden name) is a Greek surname. It is the surname of:
Evelina Papoulia (born 1971), Greek actress and dancer Georgios Papoulias (1927–2009), Greek politician and diplomat Karolos Papoulias (1929–2021), Greek politician and President of Greece Panagiotis Papoulias (born 1969), Greek runner