Saddington is a surname. Notable people with the surname include:
Col Saddington (1937–2012), Australian footballer George Saddington (born 1905), English rugby player Jason Saddington (born 1979), Australian footballer John Saddington (c.1634–1679), Muggletonian writer and London sugar merchant Nigel Saddington (born 1965), English footballer Sharron Saddington (born 1971), English musician Wendy Saddington (1949–2013), Australian singer