Sejdiu is an Albanian surname. Notable people with the surname include:
Altuna Sejdiu (born 1985), Macedonian-Albanian singer Arlind Sejdiu (born 2001), Kosovan footballer Bajrush Sejdiu (born 1968), Macedonian criminal of Albanian descent Dardan Sejdiu (born 1979), Deputy Mayor of Pristina, the capital of Kosovo Fatmir Sejdiu (born 1951), Kosovar politician and President of Kosovo Florent Sejdiu (born 1990), Albanian football player Gani Sejdiu (born 1961), Kosovan coach and former footballer Patriot Sejdiu (born 2000), Kosovan footballer Shaban Sejdiu (born 1959), Macedonian Albanian sport wrestler