HSHS may refer to: Hamilton Southeastern High School, Fishers, Indiana, United States Helensvale State High School, Helensvale, Queensland, Australia Henry-Senachwine High School, Henry, Illinois, United States Highland Springs High School, Highland Springs, Virginia, United States Hinsdale South High School, Darien, Illinois, United States Holy Spirit High School (disambiguation) Holly Springs High School, Holly Springs, North Carolina, United States Hot Springs High School (Arkansas), Hot Springs, Arkansas, United States Hot Springs High School (Montana), Hot Springs, Montana, United States Hospital Sisters Health System, Springfield, Illinois, United States