Mukwaya is a Ugandan Baganda surname, and may refer to many people.

A Abdullah Mukwaya, Qadi of Mbarara District and father of Usama Mukwaya

J Janat Mukwaya, a Ugandan politician

U Usama Mukwaya, a Ugandan film director

O Olive Kazaarwe Mukwaya, a Ugandan lawyer and judge