William Larkin may refer to:
William Larkin (painter) (died 1619), English painter William J. Larkin Jr. (1928–2019), American politician William John Larkin (died 1885), New Zealand priest, Irish nationalist and newspaper proprietor William Thomas Larkin (1923–2006), American Roman Catholic bishop Billy Stiles or William Larkin (1871–1908), American outlaw in the Old West