Mifflin is a surname. Notable people with the surname include:
Fred Mifflin (1938–2013), retired Rear Admiral in the Canadian Forces and a former politician James Mifflin (1839–?), United States Navy sailor in the American Civil War Margot Mifflin, (born 1960), U.S. Author and professor Ramón Mifflin (born 1947), Peruvian footballer Thomas Mifflin (1744–1800), American merchant and politician from Philadelphia, Pennsylvania George Harrison Mifflin (1845–1921), American publisher, co-founder with Henry Oscar Houghton of Houghton Mifflin Company
See also Mifflin (disambiguation)