Guinness () is a surname. Notable people with the surname include:
Alec Guinness (1914–2000), British actor Arthur Guinness (1725–1803), founder of Guinness beer Arthur Guinness (New Zealand politician) (1846–1913) Bunny Guinness (born 1955), British landscape architect and broadcaster Daphne Guinness (born 1967), artist Desmond Guinness (1931–2020), Irish writer on Georgian art and architecture Humphrey Patrick Guinness (1902–1986), British polo player Jasmine Guinness (born 1976), model and designer Kenelm Lee Guinness (1887–1937), racing driver and spark plug manufacturer Matthew Guinness (born 1940), British actor Oonagh Guinness (1910–1995), Anglo-Irish socialite and society hostess Os Guinness (born 1941), author Peter Guinness (disambiguation), multiple people
See also Guinness family, prominent descendants of Arthur Guinness (1725–1803) and his brother Samuel Guinness (1727–1795) Magennis