Akpan () is a Nigerian masculine given name and surname of Ibibio and Efik origin which means 'first son'.

Notable people with the name Surname Andre Akpan (born 1987), American soccer player Bassey Akpan (born 1984), Nigerian footballer Hope Akpan (born 1991), English footballer Ime Akpan (born 1972), Nigerian hurdler Rita Akpan (born 1944), Nigerian politician Uwem Akpan (born 1971), Nigerian Jesuit priest and writer

Given name Akpan Hogan Ekpo (born 1954), Nigerian economist and professor Akpan Isemin (1939–2009), Nigerian politician Akpan Okon, 18th-century African ruler Akpan Utuk, Nigerian Army colonel

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