Mesophleps safranella is a moth of the family Gelechiidae. It is found in Niger, Benin, Kenya, Malawi, Madagascar, Réunion and on the Seychelles.
The wingspan is 11.5–14 mm.
The larvae feed on Acacia species and Albizia lebbeck. They live in the pods., 2012: A taxonomic revision of the genus Mesophleps Hübner, 1825 (Lepidoptera: Gelechiidae). Zootaxa 3373: 1-82.
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