Arthur Middleton (1742–1787) was an American Revolutionary War figure.
Arthur Middleton may also refer to:
Arthur Middleton (1681–1737), acting governor of South Carolina Arthur Middleton (bass-baritone) (1880–1929), American opera singer Arthur Middleton (footballer) (1876–1945), Australian rules footballer Arthur Edward Middleton (1891–1953), British politician USS Arthur Middleton, the lead ship of the Arthur Middleton-class attack transports