Anhalonidine, also known as N-desmethylpellotine, a naturally occurring tetrahydroisoquinoline alkaloid which can be isolated from certain members of the cactus family, such as Lophophora, including notably Lophophora williamsii (peyote) (17% of alkaloid content). It is structurally related to mescaline. Anhalonidine produced no hallucinogenic effects in humans at doses of up to 250mg. However, it has been reported to have a calming or sedative effect instead, with about one-fourth the potency of pellotine and with sedation or sleepiness occurring at doses of 100 to 250mg. Anhalonidine has been found to act as a potent inverse agonist of the serotonin 5-HT7 receptor. Analogues of anhalonidine include anhalamine, anhalidine, anhalinine, gigantine, and pellotine, among others.
See also Substituted tetrahydroisoquinoline
References
External links Anhalonidine - Isomer Design Anhalonidine - Trout's Notes