Heinecke is a German surname. Notable people with the surname include:
Andreas Heinecke, German academic and activist Birgit Heinecke (born 1957), East German handball player Herman Heinecke (1869–1906), American politician Kurt Heinecke, American composer Owen Heinecke (born 2003), American football player William Heinecke (born 1949), American-born Thai businessman
See also Heinicke a similar surname