Skeen is a surname which may refer to:
Sir Andrew Skeen (1873–1935), British Indian Army general Andrew Skeen (Rhodesia) (c.1906–1984), British Indian Army officer and Rhodesian politician Buren Skeen (1936–1965), American NASCAR driver Charlie Skeen (1949–1999), American actor and stuntman Clifton Skeen (1927–1993), Ohio politician Dale Skeen (born c. 1955), American computer scientist Dick Skeen (1906–1990), American professional tennis player Henry Gene Skeen (1933–2006), U.S. Army general Jack Skeen (1928–2001), New Zealand rugby union player Jacob Skeen (born 1993), New Zealand rugby union player Jamie Skeen (born 1988), American professional basketball player Jane Skeen, New Zealand paediatric oncologist Joe Skeen (1927–2003), American politician Kasete Naufahu Skeen (born 1982), Tongan alpine skier Ken Skeen (born 1942), English footballer Mike Skeen (born 1986), American professional sports car racing driver Odean Skeen (born 1994), Jamaican sprinter W. L. H. Skeen (1847–1903), an English photographer in Ceylon (now Sri Lanka)