Simo is a surname which may refer to:
Alfredo Fernández Simó (1915–1991), Dominican novelist, poet and diplomat Ana María Simo (born 1943), New York playwright, essayist and novelist Anna Simó (born 1968), Catalan politician Augustine Simo (born 1978), Cameroonian footballer Fidji Simo (born 1985), French businesswoman Isabel-Clara Simó (1943–2020), Valencian (Spanish) journalist and writer JD Simo (born 1985), American blues and rock musician Lajos Simó (1943–2019), Hungarian former handball player Manuel Simó Marín (1868-1936), Spanish right-wing politician Mariví Simó (born 1983), Spanish football defender Sándor Simó (1934–2001), Hungarian film producer, director and screenwriter