Mompesson is a surname of English origin. Notable people with this surname includes:
Giles Mompesson (1583–1663), Member of the British Parliament (1614–1621) William Mompesson (1639–1709), Church of England clergyman Richard Mompesson (died 1627), English politician and Member of Parliament (1593) Roger Mompesson (1661 – 1715), Member of the British Parliament (1699–1701)