Khmelnytskyi () is a surname of Ukrainian origin often associated with the national hero of Ukraine Bohdan Khmelnytsky.
Notable persons Bohdan Khmelnytsky, a Hetman of Zaporizhian Host Yurii Khmelnytsky, a Hetman of Zaporizhian Host (son of Bohdan Khmelnytsky) Tymofiy Khmelnytsky (Tymish), another son of Bohdan Khmelnytsky, a Moldavian military person. Efrosinia Yanenko-Khmelnytska, niece of Bohdan Khemlnytsky and wife of Hetman Petro Doroshenko. Yurii Khmelnytsky, a brother of Bohdan Khmelnytsky Vitaliy Khmelnytskyi, a Soviet footballer and coach from the Orikhiv Raion Boris Khmelnitsky, a Soviet actor