Loose is a surname. Notable people with the surname include:
Christian Loose (born 1975), German politician Emmy Loose (1914–1987), Austrian opera singer Jacob Loose (1850–1923), American businessman Julian Loose (born 1985), German footballer Ralf Loose (born 1963), German footballer and manager Thomas Loose (born 1964), West-German slalom canoeist William Loose (1910–1991), American composer