Gayton is a surname, and may refer to:
Albert Gayton (1840–1923), Canadian merchant and politician Anna Hadwick Gayton (1899–1977), American anthropologist, folklorist and museum curator Clark Gayton, American musician Clark Gayton (1712–1785), British Royal Navy Officer Edmund Gayton (1608–1666), English academic, physician and author Howard Gayton, a founder of the Ophaboom Theatre Company Joe Gayton (c. 1956/1957–2023), American writer, director and producer Tony Gayton, American film producer and screenwriter