Nwe or Nweh is a Burmese surname. Notable people with the surname include:
Khin Moe Nwe (born 1973), Burmese weightlifter Nat Nwe (1933–2011), Burmese writer San San Nweh, Burmese writer and journalist Su Su Nwe (born 1971), Burmese democracy activist and political prisoner Yin Yin Nwe (born ), Burmese geologist