Loisel is a surname. Notable people with the surname include:
Élisabeth Loisel (born 1963), French footballer and manager Georg Loisel (born 1957), Austrian fencer Hubert Loisel (1912–1999), Austrian fencer John S. Loisel (1920–2010), American World War II flying ace Régis Loisel (born 1951), French comics writer and artist