Maupin is a French surname. Notable people with the surname include:

Armistead Maupin (born 1944), American writer Audry Maupin (1972–1994), boyfriend of Florence Rey, involved in a 1994 shoot-out in Paris Bennie Maupin (born 1940), American musician Claudia Maupin (1936–2013), American murder victim David Maupin, American gallery director and co-founder of Lehmann Maupin Gallery Harry Maupin (1872–1952), baseball pitcher Keith Matthew Maupin (1983–2004), U.S. Army soldier Robert Lee Maupin (1918–1992), also known as Robert Beck or Iceberg Slim, author Simon Maupin (before 1625–1668), French architect Thomas Maupin (born 1938), American Buck Dancer