Manderson is a surname. Notable people with the surname include:
Bert Manderson (1893–1946), Northern Irish footballer Charles F. Manderson (1837–1911), United States Senator from Nebraska Floyd Manderson (born 1961), British Olympic high jumper, Seoul Olympics 1988 Sandra Manderson, police officer and police commander from New Zealand Tobias Manderson-Galvin (born 1984), Australian actor, satirist, performance poet, dadaist and playwright Professor Green, stage name of Stephen Paul Manderson (born 1983), British rapper