Wettlaufer is a surname. Notable people with the surname include:
Boyd Wettlaufer (1914–2009), Canadian archaeologist Elizabeth Wettlaufer (born 1967), Canadian nurse and serial killer Paul Wettlaufer (born 1978), Canadian field hockey player Robin Wettlaufer, Canadian representative Ward Wettlaufer (born 1935), American golfer Wayne Wettlaufer (born 1943), Canadian politician