Ketchum is a surname that originated in England. Notable people and fictional characters with the surname include:
People Annie Chambers Ketchum (1824–1904), religious name Sister Amabilis, American educator, lecturer and writer Daniel Ketchum (born 1981), American swimmer David Ketchum (1928–2025), American actor Gerald Ketchum (1908–1992), American US Navy officer Gus Ketchum (1897–1980), American baseball player Hal Ketchum (1953–2020), American singer-songwriter Henry Ketchum (1839–1886), Canadian engineer Jack Ketchum (1946–2018), American horror writer James S. Ketchum (1931–2019), American psychiatrist Jesse Ketchum (1782–1867), Canadian tanner and politician Menis E. Ketchum (born 1943), American politician and jurist Morris Ketchum (1796–1880), American banker and financier Richard Ketchum (1773–1845), American politician Richard M. Ketchum (1922–2012), American historian and magazine editor Robert Glenn Ketchum (born 1947), American photographer Rosemary Ketchum (born 1993), American politician and community organizer Tom Ketchum (1863–1901), a.k.a. "Black Jack" Ketchum, American outlaw Wesley Harrington Ketchum (1878–1968), American physician William Ketchum (mayor) (1798–1876), American politician William M. Ketchum (1921–1978), American businessman and politician William Scott Ketchum (1813–1871), US Army officer
Fictional characters Ash Ketchum, a fictional Pokémon Trainer figure Delia Ketchum, his mother Kevin Ketchum, an OZ prisoner