GPI may refer to:

Economics Gender Parity Index Genuine progress indicator Global Payments Innovation, a faster international payment service by SWIFT

Education George Padmore Institute, a British library and archives Greenfield Park Primary International School, in Quebec, Canada

Government and politics Global Peace Index Global Partnership Initiative of the United States State Department Materiel United States national missile defense#Glide phase interceptors (GPIs)

Medicine Generic Product Identifier, a drug classification system General paresis of the insane Glucose-6-phosphate isomerase, an enzyme Glycosylphosphatidylinositol, a glycolipid Internal globus pallidus

Science and technology Gemini Planet Imager, a telescope instrument General Purpose Input, an uncommitted digital signal pin on an integrated circuit or electronic circuit board used as an input and controllable by the user at runtime. Gibson Plumage Index, an albatross identification system Global Address Space Programming Interface, a Linux API Grains per inch Granite Peak Installation, an American World-War-II-era biological weapons testing facility

Transport Glacier Park International Airport, serving Flathead County, Montana, United States Guapi Airport, in Colombia Station code for Gunung Putri railway station, in Indonesia

Other uses Glass Packaging Institute, an American trade association Global Poker Index Global Press Institute, an American journalism organization Godfrey Phillips India, an Indian tobacco company Gurley Precision Instruments, an American manufacturer

See also GP1 (disambiguation)