Gagliano () is an Italian surname. Notable people with the surname include:
Tony Gagliano (born 1958) Canadian businessman and philanthropist Alessandro Gagliano (c. 1700–1735), Italian luthier Angel Gagliano (born 1950), Argentine athlete Alfonso Gagliano (1942–2020), Canadian accountant and politician Bob Gagliano (born 1958), former American Football player Fernando Gagliano (c. 1770–1795), Italian luthier Gaetano Gagliano (1917–2016), Italian-Canadian businessman Januarius Gagliano (c. 1740–1780), Italian luthier Leonardo Gagliano (20th century), Brazilian radio speaker and sports commentator Marco da Gagliano (1582–1643), Italian composer Nicolò Gagliano (c. 1740–1780), Italian violin-maker Phil Gagliano (1941–2016), former Major League Baseball infielder Ralph Gagliano (born 1946), Major League Baseball player S. Thomas Gagliano (1931–2019), American politician Tommy Gagliano (1884–1951), Sicilian-American mobster Rico Gagliano, American journalist and podcaster