Macon is a surname. It may be derived from French Maçon or Mâcon, meaning "marsh dweller", or a variant of the occupational surname Mason.

People surnamed Macon include:

Daryl Macon (born 1995), American basketball player for Maccabi Tel Aviv of the Israeli Basketball Premier League David Harrison Macon (1870–1952), also known as Uncle Dave Macon, American country musician Eddie Macon (1927–2017), American National Football League and Canadian Football League player Gideon Macon (c. 1648–1702), early American settler and member of the House of Burgesses of Virginia Mark Macon (born 1969), American former basketball player Max Macon (1915–1989), American Major League Baseball player and minor league manager Nathaniel Macon (1758–1837), American politician Robert B. Macon (1859–1925), American politician Robert C. Macon (1890–1980), US Army general during World War II Valerie Macon (born 1950), American civil servant and eighth North Carolina Poet Laureate

See also Le Maçon, a list of people with the surname Maçon, a list of people with the surname