Hesse is a German surname. Notable people with the surname include: Adolf Friedrich Hesse (1809–1863), German composer Adukwei Hesse, Ghanaian physician-academic, tuberculosis control expert, prison reform advocate and Presbyterian minister Afua Adwo Jectey Hesse, First Ghanaian woman to train as a paediatric surgeon Amandine Hesse (born 1993), French tennis player Birgit Hesse (born 1975), German politician (SPD) Chris Tsui Hesse (born 1932), cinematographer, filmmaker, prison reform campaigner and Presbyterian minister Christian Heinrich Friedrich Hesse (1772–1832), German pastor and naturalist

Eva Hesse (1936–1970), painter and sculptor Herman Chinery-Hesse (1963–2024), Ghanaian technology entrepreneur and founder of the SOFTribe Hermann Hesse (1877–1962), German-born poet, novelist, and painter, Nobel Prize in Literature 1946

Karen Hesse (born 1952), US writer Konrad Hesse (1919–2005), German jurist Lebrecht James Chinery-Hesse (1930–2018), Ghanaian lawyer, civil servant and diplomat Lebrecht Wilhelm Fifi Hesse (1934–2000), First black African Rhodes Scholar Linda Hesse (born 1987), German singer Lo Hesse (1889–1983?), German dancer Lucien Hesse (1866–1929), French architect Mary Hesse (1924–2016), US philosopher Mary Chinery-Hesse (born 1938), Ghanaian international civil servant and diplomat, first woman Chancellor of the University of Ghana Otto Hesse (1811–1874), German mathematician, known for the Hessian matrix Parker Hesse (born 1995), American football player Paul Hesse (1857–1938), German malacologist Regina Hesse (1832–1898), pioneer woman educator-administrator in colonial Ghana Richard Hesse (1868–1944), German zoologist Ruth Hesse (1936–2024), German operatic mezzo-soprano and contralto Stefan Heße (born 1966), German Roman Catholic bishop Tyson Hesse (born 1984), American artist Virginia Hesse (born 1944), Ghanaian civil servant and diplomat Walther Hesse (1846–1911), German microbiologist

See also Ernst von Hesse-Wartegg (1851–1918), Austrian travel-author Hasse (surname) Hess (surname)