George Soule or Soulé may refer to:
George Soule (Mayflower passenger) (c. 1602–1677/80), colonist George Soulé (industrialist) (1849–1922), founder of the Soulé Steam Feed Works George Soulé (musician) (born 1945), American songwriter, musician and record producer George Henry Soule Jr. (1887–1970), labor economist and editor for the New Republic George Soule (educator) (1834–1926), Louisiana author, educator, and soldier