Harwell is a surname. Notable people with the surname include:

Beth Harwell (born 1957), American politician Corey Harwell, American neuroscientist David W. Harwell (1932–2015), American judge Ernie Harwell (1918–2010), American sportscaster Isiah Harwell (born 2007), American basketball player Jack Harwell, American sheriff Mason Harwell (1806–1879), American slave trader Robert Bryan Harwell (born 1959), American judge Steve Harwell (1967–2023), American singer and musician