Grand Isle may refer to:
Places In the United States: Grand Isle, a barrier island on the Gulf Coast, part of Jefferson Parish, Louisiana Grand Isle, Louisiana, a town located on the island Grand Isle State Park (Louisiana), a park on the island Grand Isle, Maine, a town in Maine Grand Isle (CDP), Maine, the primary village in the town Grand Isle, Vermont, a town in Vermont Grand Isle (island), an island in Vermont Grand Isle County, Vermont Grand Isle State Park (Vermont)
Other uses Grand Isle (1991 film), a film directed by Mary Lambert Grand Isle (2019 film), a film directed by Stephen Campanelli USCGC Grand Isle, a 110 ft Island Class cutter
See also Grandisle, Edmonton, Alberta, Canada Grand Island (disambiguation) Grande Île (disambiguation) Rail Car Grand Isle, an exhibition building at Shelburne Museum in Shelburne, Vermont