Glucan 1,4-α-maltohexaosidase (, exo-maltohexaohydrolase, 1,4-α-D-glucan maltohexaohydrolase) is an enzyme with systematic name 4-α-D-glucan maltohexaohydrolase. It catalyses the hydrolysis of (1→4)-α-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends

The products have the α-configuration.

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