Flier or Flyer is a surname. Notable people with the surname include:
Jaap Flier (born 1934), Dutch ballet dancer and choreographer Jeffrey Scott Flier (born 1948), American physician, endocrinologist, researcher and Dean of the Faculty of Medicine at Harvard University Manon Flier (born 1984), Dutch volleyball player Natasha Flyer (born 1969), American earth scientist and applied mathematician Yakov Flier (1912-1977), Russian concert pianist and teacher
See also Van der Flier