Mannosylfructose-phosphate phosphatase (EC 3.1.3.79, mannosylfructose-6-phosphate phosphatase, MFPP) is an enzyme with systematic name β-D-ructofuranosyl-α-D-mannopyranoside-6F-phosphate phosphohydrolase. It catalyses the following chemical reaction which removes a phosphate group (Pi) by hydrolysis:
This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires magnesium, Mg2+, for activity. The starting material is produced from GDP-mannose and fructose 6-phosphate by the enzyme mannosylfructose-phosphate synthase and the product is an osmolyte which protexts the organism from osmotic shock.
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