Derringer is a German surname. It is a variant of Deringer. Notable people with the surname include:

Robb Derringer (born 1967), American actor John Derringer ( Hayes; born 1962), Canadian radio personality Norm Derringer, common name of Norman W. Dieringer (1914–1997), American softball player Paul Derringer (1906–1987), American baseball player Rick Derringer, stage name of Richard Dean Zehringer (1947–2025), American guitarist, singer, and songwriter

In fiction Matthew Derringer, character in the American comedy web series The Most Popular Girls in School