Grumbach or von Grumbach is a surname. Notable people with the surname include:
Antoine Grumbach, French architect Argula von Grumbach (1492–1554?), Bavarian noblewoman Detlef Grumbach (born 1955), German author and journalist Doris Grumbach (1918–2022), American novelist, biographer, literary critic, and essayist Kevin Grumbach, American physician and academic Melvin M. Grumbach (1925–2016), American pediatrician and academic Wilhelm von Grumbach (1503–1567), German adventurer