Dell'Acqua is an Italian surname. Notable people with the surname include:
Gaspare dell'Acqua (active circa 1460), Italian painter of the Renaissance period, active mainly in Genoa and Pavia
Alberto Dell'Acqua (born 1938), Italian stuntman and actor Alessandro Dell'Acqua (born 1962), Italian fashion designer Angelo Dell'Acqua (1903–1972), Italian Roman Catholic cardinal Arturo Dell'Acqua Bellavitis (born 1947), the current director of the Milan Triennale Foundation and Exposition Casey Dellacqua (born 1985), Australian tennis player Cesare Dell'Acqua (1821–1905), Italian painter Eva Dell'Acqua (1856–1930), Belgian singer and composer Massimo Dell'Acqua (born 1979), Italian professional tennis player Simone Dell'Acqua (born 1989), Italian footballer