L-serine-phosphatidylethanolamine phosphatidyltransferase (, phosphatidylserine synthase 2, serine-exchange enzyme II, PTDSS2 (gene)) is an enzyme with systematic name L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase. This enzyme catalyses the following chemical reaction
L-1-phosphatidylethanolamine + L-serine L-1-phosphatidylserine + ethanolamine
This enzyme catalyses replacement of a polar head group of phosphatidylethanolamine with L-serine.
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