Cysteate synthase () is an enzyme characterised from Methanosarcinales with systematic name sulfite:O-phospho-L-serine sulfotransferase (phosphate-hydrolysing, L-cysteate-forming). It catalyses the following chemical reaction which produces L-cysteic acid by reacting phosphoserine with sulfite (), giving orthophosphate (Pi) as a byproduct:
This enzyme is a transferase containing pyridoxal-phosphate as a cofactor.
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