Boldrini is an Italian surname. Notable people with the surname include:
Andrea Boldrini (1971), Italian racing driver Arrigo Boldrini (1915–2008), Italian politician and partisan Laura Boldrini (born 1961), Italian journalist and politician, president of the Chamber of Deputies in Italy Leonardo Boldrini (16th century), Italian Renaissance painter Marcello Boldrini (1890–1969), Italian statistician Niccolò Boldrini (c.1500–c.1566), Italian Renaissance engraver