La Dépêche is the name of several newspapers:
La Dépêche du Midi, commonly known as La Dépêche, a French newspaper based in Toulouse, published 1870–present La Dépêche de Brest, a French newspaper based in Brest, 1886–1944 La Dépêche marocaine, a francophone newspaper published in Morocco 1905–1961 La Dépêche tunisienne, a francophone newspaper published in Tunisia 1892–1961 La Dépêche de Tahiti, published in Tahiti 1964–2000