Vigna is an Italian surname. Notable people with the surname include:
Albert Vigna (1891–1970), Monegasque racing cyclist Arturo Vigna (1863–1927), Italian opera conductor Benedetto Vigna (born 1969), Italian physicist and business executive Elvira Vigna (1947–2017), Brazilian writer, illustrator, and journalist Hernán Vigna (born 1977), former Argentine footballer Giovanni Vigna (born ), Italian rugby league footballer who played in the 1950s and 1960s Judith Vigna (1936–2019), English writer and painter Laura Vigna (born 1999), Italian softball player Marino Vigna (born 1938), retired Italian cyclist Pierluigi Vigna (1933–2012), Italian judge Sebastiano Vigna (born 1967), Italian professor of computer science Tecla Vigna (died 1927), Italian opera singer