Mendo is a Spanish and Portuguese given name and surname. The surnames Méndez and Mendes are derived from Mendo. An alternative Portuguese form of Mendo is Mem.

"Mendo" may refer to:

People Carlos Mendo (1933–2010), Spanish journalist (born 1949), Spanish writer Paulo Mendo (1932–2025), Portuguese politician Mendo Nunes (11th century), Portuguese nobleman Mendo Ristovski (born 1956), Australian association football player

Other uses Alternate name for Jumbee, Caribbean folk spirit Mendó, 2021 album by Alex Cuba A nickname of the food chain Mendocino Farms