David Tyrrell may refer to:
David Terrell (fighter) (born 1978), American mixed martial artist David Tyrrell (rugby league) (born 1988), Australian rugby league player David Terrell (safety) (born 1975), American football safety David Terrell (wide receiver) (born 1979), American football wide receiver David Tyrrell (physician) (1925–2005), British virologist D. Lorne Tyrrell (born 1943), Canadian physician